Play missions in this exact order to unlock the best gear, safehouses and cash bonuses before the endgame. Cross-reference with the Mission Tracker to check off each step as you go.
Following the correct GTA 6 story mission order matters more than in past titles, since several optional side activities and money methods only unlock after specific story beats, and playing out of order can cause you to miss time-limited bonuses tied to certain missions.
Act I establishes Jason and Lucia’s partnership through Welcome to Leonida, Old Friends New Problems, Small Time Hustle, The Setup, Boat Heist Prep, Squalo Run, Cleaning House, Vice Connections and Rising Tides, gradually introducing the game’s core systems. Act II shifts into higher-stakes heists starting with Port Gellhorn Job Prep and continuing through the Diamond Casino Heist, expanding the map and your crew’s ambitions.
Act III brings the story to its climax through No Way Back, Empire Building, BAWSAQ Manipulation, The Final Stand Prep and Vice City Burns, before concluding with Endgame and the Epilogue. Following this exact story mission order ensures you unlock every major reward and see all available content before finishing the campaign.